Developing a drug that is able to enter the cell and interact with its target is no mean feat, especially for large molecules. Read about how this group ‘masked’ large molecules to improve their cell permeability.
The earthy smell of soil originates from the bacteria that live there. But why do they produce this particular scent?
Tired of consuming 5 different medications a day? Read how the researchers are developing new ways to load different drugs in a single delivery system.
Instead of the wires, batteries, and light bulbs used in electric circuits, biochemical circuits use DNA and enzymes to get the job done.
Researchers developed a new way of tackling viral infection by designing nanostructures similar in shape to the virus particle.
Let’s find out how researchers are using ‘artificial intelligence’ as a tool to the advancement of drug discovery.
When cooking an egg, heat denatures proteins in the egg. How does a thermophilic bacteria prevent its proteins from denaturing too?
How do you design a “cage” for a molecule? And how do you release it again, selectively? Find out about a rationally designed red-light labile protecting group.
Mycobacteria are tough, pathogenic microbes that shield themselves with a hardy envelope known as the mycomembrane. Little is still known about the proteins that build or interact with this envelope, but these researchers are up to the challenge.
Appreciating the 3D structure of the tiny chemical compounds we work with can be really difficult – but what if you could project the structure onto your living room floor?
Chemists take a gander at how to make more appealing whole wheat loaves. For your COVID-19 baking needs and beyond!
Antibiotics are lifesaving, but current practices don’t keep them from accumulating in the environment where they can damage nature and human health. A new antibiotic design aims to solve this problem.
Their highly specialized roles of immune cells also mean they have molecular machineries that are a bit different from those in other cells, Find out here how researchers are using chemistry to advance our knowledge of one of such components, the immunoproteasome.
The COVID-19 pandemic is consuming our news feed at the moment – while you’re self-isolating read about some of the great science research going on to combat our newest virus.
The development of chemotherapy revolutionised the treatment of cancer in the 20th century, however, side effects have remained problematic. Immunotherapy, using the body’s natural immune system to fight cancer, may be a safer and more effective alternative.
Thermochemical degradation of plant matter can create a great plant fertilizer called hydrochar. But what effect does this hydrochar have on the soil ecosystem?
Ever wondered how scientists know what is going on inside a cell, or how you could design a chemical probe to tell you more? There’s a lot of things to consider, find out more here.
Could vanillin, the flavoring molecule extracted from vanilla bean, increase our body’s ability to absorb ingested drugs?
Antibodies in your body help fight disease by specifically targeting a viral or bacterial strain. This specificity makes antibodies useful for disease detection, but how do scientists reduce the chance of false positives and false negatives?
With a renewed interest in psilocybin — the psychedelic substance present in magic mushrooms — by the medical community, the Weng group at MIT sets up to study one of the enzymes that makes it.
As nanotechnology is developed into drugs for human health, scientists need to study nanoparticle clearance rates from the body.
Researchers develop an easy to use method to identify the chirality of the amino acids, amines and alcohols.
Studying membrane-bound proteins requires stabilizing their structure outside of the membrane – otherwise they fall apart. But our analytical techniques have not risen to the challenge. Sadaf et al. pushes us forward by developing novel detergents for stabilizing membrane proteins.