Category: Chemical biology

Detergents are for more than washing dishes

Studying membrane-bound proteins requires stabilizing their structure outside of the membrane – otherwise they fall apart. But our analytical techniques have not risen to the challenge. Sadaf et al. pushes us forward by developing novel detergents for stabilizing membrane proteins.

Using microbes to make natural products

Microbial systems can be a great way to make complicated products that are useful to humans. However, because the pathways to make these products involve multiple steps and can be very complex, sometimes it’s just too difficult for one species to accomplish on its own. But working as a team with another species of microbe can have its own problems. How can researchers decide which way is best?

‘Optical Tweezers’ give new insights to cancer drugs

By using a technique that allows researchers to study single molecules, scientists have gained new knowledge about how a common anti-cancer drug interacts with DNA. These findings can help explain the properties of the drug and help scientists discover novel r anti-cancer treatments with improved effectiveness.