Scientists design new molecular chaperones that can capture aggregating proteins before they cause neurodegenerative damage.
Category: Drug discovery
Discovery of Novel Compounds for the Treatment of Glaucoma: The Silent Thief of Sight
Researchers have discovered a new series of potent compounds for the treatment of glaucoma.
Using Geometry to Inhibit Signaling in Cancer Cells
Using DNA molecules to build cool structures for novel drugs.
Looking toward nature in the fight against COVID-19
How can we use compounds produced by cannabis as tools against COVID-19? This article discusses the identification of three cannabinoids which decrease the infection rate of SARS-CoV-2.
Looking into the crystal bubble
Protein crystallisation is an important technique in drug discovery, and storage of proteins in the biopharmaceutical industry but can sometimes be regarded as a dark-art. Read how researchers use air-bubbles to improve protein crystal growth.
Outsmarting the cancerous activity of cathepsin B with pH-selective peptides
Scientists showed that by modulating cathepsin B’s cleavage activity with pH-selective peptides, they can irreversibly and selectively stop its cancerous activity.