Scientists create a variety of chemical compounds and a new leaf test to investigate how the A. alternata fungi infects only the Asian pear.
Category: proteins
Drug chaperones stop proteins before they aggregate
Scientists design new molecular chaperones that can capture aggregating proteins before they cause neurodegenerative damage.
From Code to Fold – Potential of DNA in Crafting Protein Mimics
By leveraging different DNA scaffolds as templates, with variations in subunit numbers, peptide orientations, and organic junctions, researchers gain unprecedented access to untapped peptide sequence spaces.
These Engineered Microbes Recycle Greenhouse Gases to Combat Climate Change
Scientists showcase a new, large-scale method to convert harmful greenhouse gases into commercially lucrative chemicals.
Go Ask Mother Nature—she’s got an answer
An overwhelming majority of scientists are in agreement—and that never happens—something must change before we reach the so-called “point-of-no-return”. The onset of the industrial era (and the associated benefits) encouraged a system that pollutes our environment in search of the largest possible profits. More recently, our voices have gotten louder, and large groups of society have dedicated themselves to uncovering the solutions to these problems. Perhaps, in this regard, Mother Nature still has lessons to offer.
How to solve a structure
Combining different data to solve a structure
Where is the calcium? First steps toward a new MRI brain-imaging technique
Calcium is important in bones and in brains. But which brain regions have a lot of calcium? Do disease states affect calcium levels? A new tool is being developed to find out.
How to distinguish two similar chemical functional groups
Distinguishing sulfation from phosphorylation
What gives bird feathers such vivid colors?
Birds have a unique way of creating color in their wings and this is how they have become so colorful.
Prioritizing study of novel proteins
How scientists figure out what enzymes to study
Towards enzymatic hydrocarbon remediation
Towards enzymatic bioremediation of oil spills
Targeting a myosin motor to treat malaria
Title: Peptide Probes for Plasmodium falciparum MyoA Tail Interacting Protein (MTIP): Exploring the Druggability of the Malaria Parasite Motor Complex Authors: Charlie N. Saunders, Ernesto Cota, Jake Baum, and Edward W. Tate Journal: ACS Chemical Biology Year: 2020 Malaria is one of the world’s oldest known…
Looking for Viruses in Wild Bats
Cataloguing viruses in bats and other animals may help predict or trace viral transmission to humans in the future.
Polishing a Drug Lead: A Replacement for Opioids Reaches Clinical Trials
Many molecules can decrease enzymatic breakdown of our body’s natural painkillers…but which one is fit to be the best new drug?
Pathogenic E. coli Can Survive Stomach Acid…For Now
Infected cattle can transmit E. coli to humans through contaminated ground beef, but scientists are looking for a solution.
An alternative to isolating plant drugs
Discovery of the biosynthesis of a FDA-approved plant drug
Life in the Hot Springs: Bacterial Tricks for Thermal Stability
When cooking an egg, heat denatures proteins in the egg. How does a thermophilic bacteria prevent its proteins from denaturing too?
“Mix n’ Match” Metabolisms
“Jailbreaking” your smartphone is one thing—but what if you could jailbreak nature itself?
Harnessing an enzyme’s full potential by locking it in a protein cage
Researchers use a naturally crystalline protein to act as a cage to hold another enzyme. This assembly can then be used to turn waste cooking oil into biodiesel.