Category: Organic

Molecular tweezers pick viral membranes apart

While most scientists search for specific treatments for viruses like Ebola, Zika and SARS-Cov-2, non-specific methods can have broad impact. Researchers from the United States and Germany joined forces to make non-specific molecular “tweezers” that pluck pieces out of its membrane, leading to disintegrating and dead viruses.

Seeing the Invisible

Ever wondered how scientists know what is going on inside a cell, or how you could design a chemical probe to tell you more? There’s a lot of things to consider, find out more here.

Detergents are for more than washing dishes

Studying membrane-bound proteins requires stabilizing their structure outside of the membrane – otherwise they fall apart. But our analytical techniques have not risen to the challenge. Sadaf et al. pushes us forward by developing novel detergents for stabilizing membrane proteins.

Stay young with Zinc!

We might have heard that antioxidants are good for our health. They help us to fight against oxidizing agents in our body and help us to stay young!
Recently, researchers have made a new breakthrough to help us fight against the oxides even with the inactive zinc!

Painting a Fuller Picture in Medicinal Chemistry

Title: Synergistic effects of stereochemistry and appendages on the performance diversity of a collection of synthetic compounds Authors: Stu Schreiber et al. Journal: Journal of the American Chemical Society https://pubs.acs.org/doi/10.1021/jacs.8b07319 Year: 2018 The ability to rapidly evaluate what a chemical compound does to a cell, and…

A New Dichlorination of Alkenes: A Radical Twist to a Long-sought Transformation

Title: Electrocatalytic Radical Dichlorination of Alkenes with Nucleophilic Chlorine Sources Authors: Niankai Fu, Gregory S. Sauer, and Song Lin Journal: Journal of the American Chemical Society http://pubs.acs.org/doi/10.1021/jacs.7b09388 Year: 2017 The unsaturated bond of an alkene is one of the most exploited functionalities inside the organic chemist’s…