In organic chemistry, once your reaction is over you generally “work-up” the mixture. But what happens if the work-up changes the outcome?
Ibuprofen is a widely used pain killers but it isn’t administered intravenously. To make it so, scientists have modified ibuprofen slightly to alter its properties.
Researchers develop a new two-layer coating for medical devices that dramatically reduces the chance of infection.
Developing a drug that is able to enter the cell and interact with its target is no mean feat, especially for large molecules. Read about how this group ‘masked’ large molecules to improve their cell permeability.
A new synthetic method to produce melanin, the natural molecule that leads to hair color, shows promise as a safer hair dye.
How do you design a “cage” for a molecule? And how do you release it again, selectively? Find out about a rationally designed red-light labile protecting group.
Ever wondered how scientists know what is going on inside a cell, or how you could design a chemical probe to tell you more? There’s a lot of things to consider, find out more here.
Researchers have looked at the biosynthetic pathways in plants to help them synthesise the potential anti-addiction agents ibogaine and voacangine.
There’s a new record holder for the world’s blackest material. Learn about how randomly oriented carbon nanotubes can be used to create a coating darker than anything else ever made!
A clever, two-part biocatalytic strategy grants access to products of reductive amination that can be troublesome to obtain through more traditional synthetic methods.
Scientists genetically modify bacteria to overproduce uncommon antibiotics, revealing information on how bacteria regulate and modify its metabolites.
Microbial systems can be a great way to make complicated products that are useful to humans. However, because the pathways to make these products involve multiple steps and can be very complex, sometimes it’s just too difficult for one species to accomplish on its own. But working as a team with another species of microbe can have its own problems. How can researchers decide which way is best?
Amino acids were found in the Atlantis Massif, under the ocean floor. Is their non-biological synthesis the origin of life?
While discovery of new complexes can be difficult, this group at Cambridge has developed “cube traps” and effectively synthesized a molecule atkin to a molecular fidget spinner!
We have always been told that do not compare apples and oranges! They are completely different! Well a mathematical theory based on surface of material finds them similar. This theory applied by physicists in materials research has discovered new exotic phase of matter called topological materials. In this article, learn about the unique nature of this exotic phase, approaches to make these materials and their wide-spread applications.
Learn how researchers at Caltech artificially evolved proteins to synthesize some of the most challenging tiny molecules in organic chemistry!
This work reports a solvent-free solid-to-solid synthesis method for covalent organic frameworks (COFs), which is very promising from a greener and cleaner chemistry standpoint. The researchers found that hydrogen bonding within the starting material plays a key role on the porosity and crystallinity of the final COF.
Lead based perovskite is an exciting new material for solar energy, but it’s based on lead. These researchers found a way around that, making new double perovskite materials based on silver and bismuth. This new synthesis has exciting future in making perovskite solar panels into a environmentally friendly technology.
Photoredox catalysis is at it again! This time it is used to synthesize polysubstituted aldehydes – highly useful building blocks – from readily available styrenes and vinyl ethers.
Feeling disgusted by slugs? It’s ugly, wet, and giving us an unpleasant slippery sensation. Yet it is the inspiration of new chemistry innovation!
Read this article and say thanks to slugs, which have inspired scientists to invent a new glue for medical therapies!
Neural networks have been used to write fanfiction, generate pictures of fake celebrities, and draw dream-like psychedelic images from photographs. But did you know they can make chemistry easier, too?