Title: Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration Authors: Hui Shi, Xiaoxiao He, Kemin Wang, Xu Wu, Xiaosheng Ye, Qiuping Guo, Weihong Tan, Zhihe Qing, Xiaohai Yang, Bing Zhou Affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics,…
Category: Research Bites
New Organic Dye for Solar Cells
Title: An Organic D-π-A Dye for Record Efficiency Solid-State Sensitized Heterojunction Solar Cells Authors: Ning Cai§, Soo-Jin Moon‡, Le Cevey-Ha‡, Thomas Moehl‡, Robin Humphry-Baker‡, Peng Wang†, Shaik M. Zakeeruddin‡, and Michael Gratzel‡ Affiliation: †State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese…
Electrical Characterization of Si Microwires and of Si Microwire/Conducting Polymer Composite Junctions
Authors: Iman Yahyaie, Kevin McEleney, Michael Walter, Derek R. Oliver, Douglas J. Thomson, Michael S. Freund, and Nathan S. Lewis Affiliation: California Institute of Technology Journal: Journal of Physical Chemistry Letters A holy grail of chemical energy technology is the development of an artificial photosynthetic cell…
Chlorination of Dodecaborate Under Mild Conditions and Sebsequent Catalytic Hydrodefluorination
Title: Exhaustive Chlorination of [B12H12]2- without Chlorine Gas and the Use of [B12H12]2- as a Supporting Anion in Catalytic Hydrodefluorination of Aliphatic C-F Bonds Authors: Weixing Gu and Prof. Oleg Ozerov Journal: Inorganic Chemistry Affiliation: Department of Chemistry, Texas A&M University Synthesis of [B12Cl12]2- from [B12H12]2-,…
Graphite nanofibers as support for fuel cell catalyst
Title: Surface-reconstructed graphite nanofibers as a support for cathode catalysts of fuel cells Journal: Chemical Communications, 2011, ASAP Authors: Lin Gana,b, Hongda Dua, Baohua Lia, and Feiyu Kanga,b Affiliation: aInstitute of Advanced Materials, Graduate School at Shenzhen, Tsinghua University; bLaboratory of Advanced Materials, Department of Materials…
Attaching small molecules to the Staphylococcus aureus cell wall
A Biosynthetic Strategy for Re-engineering the Staphylococcus aureus Cell Wall with Non-native Small Molecules James W. Nelson, Alexander G. Chamessian, Patrick J. McEnaney, Ryan P. Murelli, Barbara I. Kazmiercak, David A. Spiegel* Departments of Chemistry and Medicine, Yale University, New Haven, CT ACS Chem. Bio. 2010,…
A synthesis of strychnine by a longest linear sequence of six steps
A synthesis of strychnine by a longest linear sequence of six steps David B. C. Martin and Christopher D. Vanderwal* Department of Chemistry, University of California, Irvine Chemical Science, Advanced Article Strychnine, a crystalline alkaloid known to most as a powerful toxin used in pesticides, has…
Distinguishing Between Pathways for Transmetalation in Suzuki-Miyaura Reactions
Distinguishing Between Pathways for Transmetalation in Suzuki-Miyaura Reactions Brad P. Carrow and John F. Hartwig* J. Am. Chem. Soc. 2011, 133, 2116. The Suzuki-Miyaura cross-coupling reaction (Fig. 1) is definitely one of the most important reactions in synthetic chemistry, especially in industrial and medical settings. So…
Activating efficient phosphorescence from purely organic materials by crystal design
Journal: Nature Chemistry Authors: Onas Bolton, Kangwon Lee, Hyong-Jun Kim, Kevin Y. Lin, and Jinsang Kim Affiliation: University of Michigan, Ann Arbor Phosphorescent materials, those which emit light long after excitation, have found increasing use in organic electronics as well as chemical and biological sensing. Perhaps…
Trinuclear Copper Complex
Title: Trinucleating Copper: Synthesis and Magnetostructural Characterization of Complexes Supported by a Hexapyridyl 1,3,5-Triarylbenzene Ligand Authors: Emily Y. Tsui, Dr. Michael W. Day, Prof. Theodor Agapie Journal: Angewandte Chemie International Edition Affiliation: Division of Chemistry and Chemical Engineering, California Institute of Technology Cartoon of the Trinuclear Copper…
Cu(II) coordination in Proteins
Coordination Features and Affinity of the Cu2+ site in the alpha-Synuclein Protein of Parkinson’s Disease Dudzik, C.G.; Walter, E.D. and Millhauser, G.L. Biochemistry ASAP Alpha-synuclein proteins, concentrated in neurons in the human body, are composed of mostly hydrophobic residues. The hydrophobicity of the protein results in…
MRI agent for imaging myelin
Title: A Myelin-Specific Contrast Agent for Magnetic Resonance Imaging of Myelination Journal: Journal of the American Chemical Society Authors: Luca Frullano*, Changning Wang*, Robert H. Miller**, and Yanming Wang* Affiliation: *Division of Radiopharmaceutical Science, Case Center for Imaging Research, Department of Radiology, and **Department of Neuroscience,…
DNA film with light switching capabilities
Title: Preparation of [Ru(bpy)2(dppz)]2+-Intercalated DNA Cast Films Using a Self-Standing Method and Its Luminescence Tuning by Cu2+ Ions and EDTA Journal: Inorganic Chemistry Authors: Miojing Chen,* Hong Li,* Jiangyan Shao,* Yan Huang,* and Zheng Xu** Affiliation: *Key Lab of Technology on Electrochemical Energy Storage and Power…
Anti-cancer nanomaterials
Title: Photothermally Enhanced Drug Delivery by Ultrasmall Multifunctional FeCo Journal: ACS Nano Authors: Sarah P. Sherlock, Scott M. Tabakman, Liming Xie, and Hongjie Dai Affiliation: Stanford University, Department of Chemistry Nanomaterials have a wide variety of uses and we have just begun to discover their capabilities. They…