What can you do with a glucose meter?

More than you might think! Researchers have “hacked” glucose meters to detect enzymes, bacteria, and viruses using a device millions of people already use every day.

‘Optical Tweezers’ give new insights to cancer drugs

By using a technique that allows researchers to study single molecules, scientists have gained new knowledge about how a common anti-cancer drug interacts with DNA. These findings can help explain the properties of the drug and help scientists discover novel r anti-cancer treatments with improved effectiveness.

Using chemical probes to identify bacterial virulence factors

It seems like a silly question: how can we study the function of proteins with unknown functions? The answer: with activity-based chemical probes. In this article, researchers identified several previously unexplored enzymes that may play a role in serious bacterial infections.

Painting a Fuller Picture in Medicinal Chemistry

Title: Synergistic effects of stereochemistry and appendages on the performance diversity of a collection of synthetic compounds Authors: Stu Schreiber et al. Journal: Journal of the American Chemical Society https://pubs.acs.org/doi/10.1021/jacs.8b07319 Year: 2018 The ability to rapidly evaluate what a chemical compound does to a cell, and…

3 questions explaining “What, Where and How” of the new exotic phase of matter – TOPOLOGICAL MATERIALS

We have always been told that do not compare apples and oranges! They are completely different! Well a mathematical theory based on surface of material finds them similar. This theory applied by physicists in materials research has discovered new exotic phase of matter called topological materials. In this article, learn about the unique nature of this exotic phase, approaches to make these materials and their wide-spread applications.

Scanning for Skin Cancer

The idea that a full body scan can give comprehensive medical prognosis may be closer than we realize. Scanning mass spectrometry has been used to differentiate between healthy and cancerous skin cells. We can literally scan a person for skin cancer!

Destroying Rogue Kinases with Degraders

Aberrant enzyme activity drives many types of cancer and other human diseases. Traditional drugs targeting such enzymes face a variety of challenges. Here, researchers use a new small molecule “degrader” to destroy an enzyme involved in cancer.