The First Chemical Synthesis of Griffipavixanthone: Bringing out Intellectual and Artistic Virtuosity in Synthetic Chemistry

How do synthetic chemists use fundamental, yet robust reactions to chemicals stitch together smaller fragments large and complex natural products? The Porco's Lab latest work might give you a taste of what it's like to exercise the art of total synthesis with a hint of inspiration from biology.


Alternative Fuel Production by a Cu-Zr Inorganic Sponge

Cu oxide clusters deposited on the ZrO2 nodes of NU-1000 by AIM catalyze partial oxidation of methane. The state of the Cu was determined by XAS analysis to contain ∼15% Cu+ and ∼85% Cu2+ under ambient conditions. The average structure of the Cu is square planar coordinated by four O atoms (Cu−O ≈ 1.94 Å) with an additional one or two out-of-plane Jahn−Tellerdistorted O atoms, one of them has Cu−O ≈ 2.33 Å). A Cu− Cu distance of ∼2.93 Å was observed and the coordination number of Cu was determined at 1.3 ± 0.3. A combined EXAFS and DFT study indicates that the cluster that predominates in Cu-NU-1000 is likely to be a trimeric Cu-hydroxide-like structure that bridges two nodes across the c-pore of the MOF.

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