MACHINE LEARNING TECHNIQUES UNRAVEL CELL DEATH MARKERS

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Title: Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 ImmunostainingAuthors: Jenny Jin, Kenji Schorpp, Daniel Samaga, Kristian Unger, Kamyar Hadian, and Brent R. StockwellYear: 2022Journal: ACS Chemical BiologyDOI: https://doi.org/10.1021/acschembio.1c00953 Featured image by Alex Ritter, Jennifer Lippincott Schwartz and Gillian Griffiths, National Institutes of…

Go Ask Mother Nature—she’s got an answer

An overwhelming majority of scientists are in agreement—and that never happens—something must change before we reach the so-called “point-of-no-return”. The onset of the industrial era (and the associated benefits) encouraged a system that pollutes our environment in search of the largest possible profits. More recently, our voices have gotten louder, and large groups of society have dedicated themselves to uncovering the solutions to these problems. Perhaps, in this regard, Mother Nature still has lessons to offer.

A hand drawing fairy lights from a clear mason jar in the dark

Identifying toxic pesticides with microbial electricity

Some pesticides function similarly to the nerve agent sarin, and their ubiquitous use makes them a constant health hazard if unmonitored. Chemists designed a dual-microbe sensor to selectively and sensitively determine when the hazardous chemicals are nearby.

Breaking down the study descriptors in a clinical trial

Clinical trials are often labeled with a laundry list of descriptors: single blind, double blind, placebo-controlled, randomized – what do these labels all mean? Let’s look at a recent study as an example of what these descriptions mean and why they’re relevant to the research conducted.

Unmasking COVID-19 infections

As the global COVID-19 pandemic rolls into its third year many of us wear masks almost all day at work or in the community. Read how these researchers have developed a sensor that can be embedded into your mask, which collects your exhaled breath to act as a COVID-19 test for the end of the day.

Molecular Nanoparticles: Large Molecules to Prevent Oxidative Stress?

Maybe chemistry can save us—in this case, synthetic chemists have developed a family of lanthanide-oxo molecules and investigate their capabilities as radical species scavengers, with a possible future in the clinic to mitigate various diseases onset by oxidative stress (get antioxidants into your diet, people!).

Ozone Is The Key To Effective Lipid Detection And Isomer Resolution

Lipids are an important class of biological molecules where the physical and chemical structure will impact its function in our body. Effective lipid detection and analysis are key to understanding specific lipid interactions and overall biological impact. This paper discusses development of new analytical detection technique for mass spectrometry which provides greater insight into lipid biological chemistry.

Getting Rare (Earth) Elements via Proteins

Title: Bridging Hydrometallurgy and Biochemistry: A Protein-Based Process for Recovery and Separation of Rare Earth Elements https://doi.org/10.1021/acscentsci.1c00724 Rare earth elements (REEs), i.e. the lanthanides, yttrium, and scandium, are used in many critical parts of modern life due to their electromagnetic properties, including healthcare, consumer electronics, and…