Finding new antibiotics is difficult. Synthesising those new antibiotics can be just as hard, and sometimes is takes a long time to find a good approach. And sometimes the most important step in synthesis optimisation is characterising your side-products.
In diabetics, insulin production is reduced as a protease inactivates GLP1 responsible for insulin production. Administration of GLP1 could help, but it needs to be altered to sneak past the protease.
The antibiotics we take are beginning to build up in the environment. Researchers are beginning to look into different ways of removing those antibiotics, and subsequently reducing the harm to our environment, with varying degrees of success.
Title: Peptide Probes for Plasmodium falciparum MyoA Tail Interacting Protein (MTIP): Exploring the Druggability of the Malaria Parasite Motor Complex Authors: Charlie N. Saunders, Ernesto Cota, Jake Baum, and Edward W. Tate Journal: ACS Chemical Biology Year: 2020 Malaria is one of the world’s oldest known…
Binding of the spike protein is essential for the immune response generated from many COVID-19 vaccines. Mutations on this protein may pose a threat to the efficacy and reliability of our current vaccination strategies.
Amino acids found on meteorites may have seeded the beginnings of life on Earth, but where do they come from? Based on their isotopic signatures, they may have come from interstellar space.
Your blood is made up of many different proteins, and the concentrations of these proteins are different in healthy individuals and cancer patients. By exploiting these differences, researchers have developed a new method for diagnosing lung cancer using just a simple blood test.
Using nanofibers to create biosensors decreases cost and wrapping them in graphene increases their conductivity.
Cataloguing viruses in bats and other animals may help predict or trace viral transmission to humans in the future.
What technology is currently in use to remove carbon dioxide from the atmosphere? What technologies lie ahead to help us catch up to our emissions?
Two proteins in the surface of GAS bacterium are able to bind to damaged collagen. Thus facilitating the infection of this pathogen in wounds.
Title: Organophosphate Diesters in Urban River Sediment from SouthChina: Call for More Research on Their Occurrence and Fate in FieldEnvironment Authors: Chan Liang, Bo Peng, Gao-Ling Wei, Yanyan Gong, Guoqiang Liu, Lixi Zeng, Liang-Ying Liu, and Eddy Y. Zeng Journal: ACS EST Water 2021, 1, 4, 871–880 Organophosphate triesters are used as flame retardants, as well as…
Primary source information: Title: Impact of wet-dry cycling on the phase behavior and compartmentalization properties of complex coacervates Authors: Hadi M. Fares, Alexander E. Marras, Jeffrey M. Ting, Matthew V. Tirrell, and Christine D. Keating. Journal: Nat Commun 11, 5423 (2020) Think about combining oil and…
Half-a-billion-year-old molecular skeletons tell conflicting stories about the first animals that evolved on Earth.
Researchers develop a new two-layer coating for medical devices that dramatically reduces the chance of infection.
Computation has a way of finding its use in every field, and drug discovery isn’t exempt from it, especially when we are time-bound.
Usually e-liquid has 4 ingredients listed – propylene glycol, glycerol, nicotine, and flavoring. However, the ingredients at the time of manufacturing do not necessarily reflect what you inhale in the aerosol. The ingredients can degrade to aldehyde products, which are highly reactive and may cause toxic outcomes for our cells.
CFC-11 is an industrially useful but ozone depleting chemical. The recently reported decline in global CFC-11 emissions grants the ozone layer a reprieve to heal.
Researchers meld ideas from biology and chemistry to generate hybrid catalysts that can catalyze natural reactions at even faster rates.
Sometimes we see a paper heading and freak out, put the paper away and never return to it. But don’t worry if that’s the case, we’ve got you…
The chemical composition of meteorites provides important information about which building blocks might have been available for the origin of life on Earth.
Many of us have first-hand experience with how hard it can be to get ice off things when you can’t melt it. Researchers have used the electrostatic charge in ice to make it jump, creating a new avenue for de-icing in the future.