Scientists showed that by modulating cathepsin B’s cleavage activity with pH-selective peptides, they can irreversibly and selectively stop its cancerous activity.
Author: Lauren Gandy
Lauren is a PhD candidate of chemistry at Rensselaer Polytechnic Institute, studying the structural interactions of several protein-protein, protein-glycan and protein-small molecule interactions using various biophysical techniques. She obtained her B.S. in Forensic Biochemistry at the University of Central Florida in 2017.
Molecular tweezers pick viral membranes apart
While most scientists search for specific treatments for viruses like Ebola, Zika and SARS-Cov-2, non-specific methods can have broad impact. Researchers from the United States and Germany joined forces to make non-specific molecular “tweezers” that pluck pieces out of its membrane, leading to disintegrating and dead viruses.
Boiling mulberry juice increases its anti-cancer properties
Black mulberry juice is a known antioxidant – compounds that can consume free radicals before they can harm your cells. Researchers at Guangdong University also show that boiling mulberries increases its ability to treat colon cancer in cell culture, but not through antioxidant mechanisms.
#BlackInChem: Creating Support and Community for Black Women in STEM
Devin Swiner, one of the founders for #BlackInChem, shares what’s she’s learned, the hard-won wisdom she has earned as a Black woman in analytical chemistry.
Monitoring plant maturation with a Wack reaction
When the authors’ blurb about their own work is “Okay, bloomer,” you know you have to read it.
Want fluffy whole wheat bread? Use smaller flour particles
Chemists take a gander at how to make more appealing whole wheat loaves. For your COVID-19 baking needs and beyond!
Make it green, make it bright!
Scientists craft a “greener,” copper-iodide-based ink with amazingly efficient photoluminescent properties
Vanilla substitute loosens up cell membranes to increase drug uptake
Could vanillin, the flavoring molecule extracted from vanilla bean, increase our body’s ability to absorb ingested drugs?
Detergents are for more than washing dishes
Studying membrane-bound proteins requires stabilizing their structure outside of the membrane – otherwise they fall apart. But our analytical techniques have not risen to the challenge. Sadaf et al. pushes us forward by developing novel detergents for stabilizing membrane proteins.
Now slide real smooth: Using peptide coatings to prevent biofilm formation
When it comes to milk, preventing bacterial contamination on dairy equipment is key. Researchers in Israel developed a biological coating to prevent biofilm formation and keep their moo-juice fresh and clean.
Delicious diagnosis – real-time glucose analysis straight from your gut
Scientists from UCSD and Compultense University developed non-invasive tools to measure gastrointestinal distress, monitoring chemical markers in real-time.
Light me up: can visible light impact forensic luminol reactions?
Crime scene techs use luminol to reveal latent bloodstains – can normal, visible light increase the reaction’s sensitivity?
Manipulating actinomycetes for unusual antibiotics
Scientists genetically modify bacteria to overproduce uncommon antibiotics, revealing information on how bacteria regulate and modify its metabolites.
Fishing for bacteria with gold and DNA
What happens when you bring DNA strands, gold nanoparticles, conformation-induced color changes, and a highly-intrusive bacterium together? A field-portable, inexpensive test for the world’s greatest bacterial threats.