Author: Emilia

Painting a Fuller Picture in Medicinal Chemistry

Title: Synergistic effects of stereochemistry and appendages on the performance diversity of a collection of synthetic compounds Authors: Stu Schreiber et al. Journal: Journal of the American Chemical Society Year: 2018 The ability to rapidly evaluate what a chemical compound does to a cell, and…

New Findings on Viral Inhibition

Successful resistance to a viral infection requires the host to deploy incredibly intricate biological tactics that somehow selectively inhibit key processes in the viral lifecycle. In this paper, researchers delve deeper into the molecular mechanisms of one of such resistance mechanisms!

A New Dichlorination of Alkenes: A Radical Twist to a Long-sought Transformation

Title: Electrocatalytic Radical Dichlorination of Alkenes with Nucleophilic Chlorine Sources Authors: Niankai Fu, Gregory S. Sauer, and Song Lin Journal: Journal of the American Chemical Society Year: 2017 The unsaturated bond of an alkene is one of the most exploited functionalities inside the organic chemist’s…

The First Chemical Synthesis of Griffipavixanthone: Bringing out Intellectual and Artistic Virtuosity in Synthetic Chemistry

How do synthetic chemists use fundamental, yet robust reactions to chemicals stitch together smaller fragments large and complex natural products? The Porco’s Lab latest work might give you a taste of what it’s like to exercise the art of total synthesis with a hint of inspiration from biology.