Category: Biological

Duality of Iron Oxide Nanoparticles in Cancer Therapy

Title: Duality of Iron Oxide Nanoparticles in Cancer Therapy: Amplification of Heating Efficiency by Magnetic Hyperthermia and Photothermal Bimodal Treatment Authors: Ana Espinosa, Riccardo Di Corato, Jelena Kolosnjaj-Tabi, Patrice Flaud, Teresa Pellegrino, and Claire Wilhelm DOI 10.1021/acsnano.5b07249 By: Ehsan Moaseri – Behzad Changalvaie In our previous…

Health Assessment in Your Home via Disposable Breath Analysis Sensors

Title: Diagnosis and Classification of 17 Diseases from 1404 Subjects via Pattern Analysis of Exhaled Molecules Authors: Hossam Haick et al. Publication Info: ACS Nano, 2017, 11 (1), pp 112–125 DOI: 10.1021/acsnano.6b04930 This work reports on the development of a portable, inexpensive, and non-invasive breath analyzer that couples the use…

Future of Cancer Therapy: Advanced Functional Nanomaterials to Image and Deliver Drugs into Tumors

Title: Controlled Assembly of Biodegradable Plasmonic Nanoclusters for Near-Infrared Imaging and Therapeutic Applications Authors: Jasmine M. Tam, Justina O. Tam, Avinash Murthy, Davis R. Ingram, Li Leo Ma, Kort Travis, Keith P. Johnston, and Konstantin V. Sokolov Journal: ACS Nano Gold has been historically a great…

Using Biology to Harness the Power of Fluorine Chemistry

What comes to mind when you think of fluorine? The sodium fluoride in toothpaste and mouthwash is the typical, everyday example that most people think of, but fluorine plays a large role in many other compounds. Pure fluorine is a highly reactive and poisonous gas, while fluorinated compounds are incredibly stable, fairly nontoxic, and used in many real-life applications.

Can adding calcium help forests?

This study further supports a connection between acid deposition and forest decline. The authors state, “Continued vigilance in the control of acid rain precursors will be needed to correct these problems, and aggressive options to reduce pollution in rapidly industrializing regions of Latin America, Asia, and Africa are warranted.”

Prettier than dyed eggs?

The cocoons, the silkworm itself, and the produced silk become colored when dye is incorporated into the silkworm feed. The concentration of dye in the produced silk changes based on how hydrophobic the dye is (increasing partition coefficient).

Using photochemistry to attach and release biomolecules in hydrogels

Title: Photoreversible Patterning of Biomolecules within Click-Based Hydrogels Authors:  Cole A. DeForest and Kristi S. Anseth Journal: Angewandte Chemie International Edition Affiliation: Chemical & Biological Engineering, University of Colorado and the Howard Hughes Medical Institute   Hydrogels have become an important category of materials for studying…

Thanksgiving chemistry- cranberries and your blood

To do the biological study of how particular (good) chemicals like antioxidants affect people, there needs to be a quick, reliable, and consistent way to measure those chemicals in humans. Furthermore, a good method would test for multiple chemicals, because the health benefits from some chemicals only exist in the presence of others (phenolic acids and flavonoids in this case). The authors of this paper demonstrate a gas-chromatography mass-spectrometry (GC-MS) method to investigate how some of the chemicals present in cranberries (from cranberry juice) go into your bloodstream after you ingest them.

Sensing Potassium

Title of Post: Sensing Potassium Title:  A New Highly Selective Fluorescent K+ Sensor Authors: Xianfeng Zhou, Fengyu Su, Yanqing Tian, Cody Youngbull, Roger H. Johnson, and Deirdre R. Meldrum Journal: Journal of the American Chemical Society Affiliation: Center for Biosignatures Discovery Automation, Biodesign Institute, Arizona State…

Hybrid Photocatalyst for Hydrogen Production

Title: Nature-Driven Photochemistry for Catalytic Solar Hydrogen Production: A Photosystem I–Transition Metal Catalyst Hybrid  Authors: Lisa M. Utschig, Sunshine C. Silver, Karen L. Mulfort, and David M. Tiede Journal: Journal of the American Chemical Society Affiliation: * Chemical Sciences and Engineering Division, Argonne National Laboratory, Argonne, Illinois…

Toward Functional Ni-SOD Biomimetics: Achieving a Structural/Electronic Correlation with Redox Dynamics

Title: Toward Functional Ni-SOD Biomimetics: Achieving a Structural/Electronic Correlation with Redox Dynamics Authors: Eric M. Gale†, Andrew C. Simmonett†, Joshua Telser‡, Henry F. Schaefer, III†, and Todd C. Harrop*† Journal: Inorganic Chemistry Affiliation: Department of Chemistry and Center for Computational Chemistry, The University of Georgia Department of Biological, Chemical and…

A Protein-Based Approach for DNA Damage Sensing

Title: Turn-On DNA Damage Sensors for the Direct Detection of 8-Oxoguanine and Photoproducts in Native DNA             Authors: Jennifer L. Furman, Pui-Wing Mok, Ahmed H. Badran, and Indraneel Ghosh* Journal: Journal of the American Chemical Society Affiliation: Department of Chemistry and…

What chirality can do for your hydrogel

Title: Enhanced Mechanical Rigidity of Hydrogels Formed from Enantiomeric Peptide Assemblies Authors: Katelyn J. Nagy†‡, Michael C. Giano†‡, Albert Jin§, Darrin J. Pochanǁ, and Joel P. Schneider† Journal: Journal of the American Chemical Society Affiliation: †National Cancer Institute, Center for Cancer Research; ‡University of Delaware, Department…

New Hydrogels from Peptide Sequences Found in Nature

Title: Supramolecular hydrogels based on the epitope of potassium ion channels Authors: Yi Kuang, Yuan Gao, Junfeng Shi, Hsin-Chieh Lin and Bing Xu Journal: Chemical Communications Affiliation: Department of Chemistry, Brandeis University Supramolecular hydrogels are a growing field of research due to their biocompatibility and the…

Intrinsic Proton-Donating Power of Zinc-Bound Water in a Carbonic Anhydrase Active Site Model Estimated by NMR

Title: Intrinsic Proton-Donating Power of Zinc-Bound Water in a Carbonic Anhydrase Active Site Model Estimated by NMR Authors: Stepan B. Lesnichin†‡, Ilya G. Shenderovich*†‡, Titin Muljati†, David Silverman, and Hans-Heinrich Limbach*† Journal: Journal of the American Chemical Society Affiliation: †Institut für Chemie und Biochemie, Freie Universität Berlin ‡Department…

Synthetic manganese–calcium oxides mimic the water-oxidizing complex of photosynthesis functionally and structurally

Title: Synthetic manganese–calcium oxides mimic the water-oxidizing complex of photosynthesis functionally and structurally Authors: Ivelina Zaharieva, M. Mahdi Najafpour, Mathias Wiechen, Michael Haumann, Philipp Kurz and Holger Dau Journal: Energy and Environmental Science, 2011, 4, 2400-2408 Published: March 3, 2011 Main Affiliations: Fachbereich Physik, Freie Universität…

Drug Delivery via Hydrogels

Title: Self-assembling peptide–polysaccharide hybrid hydrogel as a potential carrier for drug delivery Authors: Renliang Huang, Wei Qi, Libin Feng, Rongxin Su and Zhimin He Journal: Soft Matter Affiliation: State Key Laboratory of Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University Hydrogels are big networks…

The Crystal Structure of Photosystem II

Title: Crystal Structure of oxygen-evolving photosystem II at a resolution of 1.9 angstroms  Authors: *Yasufumi Umena, +Keisuke Kawakami, +Jian-Ren Shen, and *Nobou Kamiya Journal: Nature Affiliation: *Department of Chemistry, Graduate School of Science, Osaka City University. + Division of Bioscience, Graduate School of Natural Science and…

Gold Nanorods for Therapeutics

Title:  Light Interactions with Gold Nanorods and Cells: Implications for Photothermal Nanotherapeutics Journal: Nano Letters Authors: Constantin Ungureanu†, Rene Kroes†, Wilma Petersen†, Tom A. M. Groothuis‡, Felicia Ungureanu‡, Hans Janssen§, Fijs W. B. van Leeuwen, Rob P. H. Kooyman‡, Srirang Manohar†, and Ton G. van Leeuwen†…

DNA charge transport over 34 nm

Title: DNA charge transport over 34 nm Authors: Jason D. Slinker, Natalie B. Muren, Sara E. Renfrew and Jacqueline K. Barton* Affiliation: Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California Journal: Nature Chemistry, 3, 230-235 (2011) | doi: 10. 1038/nchem.982 In the…

Aptamer probes for in vivo cancer imaging

Title: Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration Authors: Hui Shi, Xiaoxiao He, Kemin Wang, Xu Wu, Xiaosheng Ye, Qiuping Guo, Weihong Tan, Zhihe Qing, Xiaohai Yang, Bing Zhou Affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics,…