A Chinese research group has employed a chemical proteomic strategy to determine the mechanism of action of the anti-inflammatory molecule itaconate. Itaconate non-enzymatically modifies cellular proteins in order to modulate their activity, leading to a reduction in the activation of immune cells, which could pave the way to an autoimmune therapy.
Nothing compares to a well-trained dog’s nose for smelling out faint odors. But a new artificial nose made with living cells may come close!
Fluorescent proteins are incredibly useful for exploring the inside of living cells. Let’s learn about a new way to find better-performing proteins using machine learning!