Tag: organic chemistry

How a Small, Organic Molecule Reigns in the Immune System

Featured Image Source: https://pixabay.com/illustrations/bacteria-illness-virus-infection-163711/ Primary Source Info Title: S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate Authors: Wei Qin, Ke Qin, Yanling Zhang, Wentong Jia, Ying Chen, Bo Cheng, Linghang Peng, Nan Chen, Yuan Liu, Wen Zhou, Yan-Ling Wang, Xing Chen, Chu Wang Year: 2019…

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Seeking inspiration from nature to treat opioid addiction

Paper: Biosynthesis of an Anti-Addiction Agent from the Iboga Plant. https://pubs.acs.org/doi/10.1021/jacs.9b05999Authors: Scott C. Farrow, Mohamed O. Kamileen, Lorenzo Caputi, Kate Bussey, Julia E. A. Mundy, Rory C. McAtee, Corey R. J. Stephenson, Sarah E. O’ConnorJournal: Journal of the American Chemical societyYear: 2019Doi: https://doi.org/10.1021/jacs.9b05999 Featured Image adapted…

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Detergents are for more than washing dishes

Studying membrane-bound proteins requires stabilizing their structure outside of the membrane – otherwise they fall apart. But our analytical techniques have not risen to the challenge. Sadaf et al. pushes us forward by developing novel detergents for stabilizing membrane proteins.

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The Smell of Success

Although skunks are nocturnal animals that prefer their own company, they won’t hesitate to spray potential predators, people or pets with fluid from their anal glands. For many years, these anal secretions have fascinated natural products chemists but repelled most of the rest of us. Learn about a new way to “de-skunk” from researchers at the University of Oklahoma.

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Can Chemists Cure the Common Cold?

Although getting the common cold is not a nice experience, it is only a relatively minor misfortune for most people. But the consqeuences of a cold can be severe. This paper describes a significant step towards a cure!

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How do you stick hydrophilic and hydrophobic molecules to each other?

We know that complementary functional groups are needed for strong intermolecular interactions, and that thermodynamics favours hydrophilic and hydrophobic groups each keeping themselves to themselves. So, problems can arise when trying to react very hydrophilic and very hydrophobic molecules together. This group of scientists has devised a way around the problem using a technique called solid-phase synthesis.

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