Distinguishing sulfation from phosphorylation
Ibuprofen is a widely used pain killers but it isn’t administered intravenously. To make it so, scientists have modified ibuprofen slightly to alter its properties.
If your DNA is a cookbook of “recipes” your cells could make, microRNAs help decide what’s for dinner.
Malaria is one of the world’s oldest known diseases. In the second century, Romans were advised to wear amulets to protect themselves against the mal aria, or “bad air.” Unsurprisingly, this was ineffective against the surrounding wetlands that were infested with mosquitoes – mosquitoes that we…
Cataloguing viruses in bats and other animals may help predict or trace viral transmission to humans in the future.
Researchers develop a new two-layer coating for medical devices that dramatically reduces the chance of infection.
Many molecules can decrease enzymatic breakdown of our body’s natural painkillers…but which one is fit to be the best new drug?
With a growing interest in the field of RNA-targeted therapeutics, robust platforms to study RNA small-molecule interactions are needed. Read about the latest endeavor here!
Infected cattle can transmit E. coli to humans through contaminated ground beef, but scientists are looking for a solution.
Developing a drug that is able to enter the cell and interact with its target is no mean feat, especially for large molecules. Read about how this group ‘masked’ large molecules to improve their cell permeability.
The earthy smell of soil originates from the bacteria that live there. But why do they produce this particular scent?
Tired of consuming 5 different medications a day? Read how the researchers are developing new ways to load different drugs in a single delivery system.
Instead of the wires, batteries, and light bulbs used in electric circuits, biochemical circuits use DNA and enzymes to get the job done.
Researchers developed a new way of tackling viral infection by designing nanostructures similar in shape to the virus particle.
Let’s find out how researchers are using ‘artificial intelligence’ as a tool to the advancement of drug discovery.
When cooking an egg, heat denatures proteins in the egg. How does a thermophilic bacteria prevent its proteins from denaturing too?
How do you design a “cage” for a molecule? And how do you release it again, selectively? Find out about a rationally designed red-light labile protecting group.
Mycobacteria are tough, pathogenic microbes that shield themselves with a hardy envelope known as the mycomembrane. Little is still known about the proteins that build or interact with this envelope, but these researchers are up to the challenge.
Appreciating the 3D structure of the tiny chemical compounds we work with can be really difficult – but what if you could project the structure onto your living room floor?
Chemists take a gander at how to make more appealing whole wheat loaves. For your COVID-19 baking needs and beyond!
Antibiotics are lifesaving, but current practices don’t keep them from accumulating in the environment where they can damage nature and human health. A new antibiotic design aims to solve this problem.
Their highly specialized roles of immune cells also mean they have molecular machineries that are a bit different from those in other cells, Find out here how researchers are using chemistry to advance our knowledge of one of such components, the immunoproteasome.