How can using computational and biochemical techniques help us understand the different flavors of cannabis? This paper explores identifying terpenes that make each cannabis strain unique.
Lipids are an important class of biological molecules where the physical and chemical structure will impact its function in our body. Effective lipid detection and analysis are key to understanding specific lipid interactions and overall biological impact. This paper discusses development of new analytical detection technique for mass spectrometry which provides greater insight into lipid biological chemistry.
Protein crystallisation is an important technique in drug discovery, and storage of proteins in the biopharmaceutical industry but can sometimes be regarded as a dark-art. Read how researchers use air-bubbles to improve protein crystal growth.
Calcium is important in bones and in brains. But which brain regions have a lot of calcium? Do disease states affect calcium levels? A new tool is being developed to find out.
Scientists showed that by modulating cathepsin B’s cleavage activity with pH-selective peptides, they can irreversibly and selectively stop its cancerous activity.
We will continue coming across new viral proteins and viruses, so it doesn’t hurt to be prepared for those. The work of White et al helps in giving a starting point for medicines against the Influenza viruses.
Avocado peels and uprooted invasive plants can become a source for anti-inflammatories. I’ll toast to that!
Ibuprofen is a widely used pain killers but it isn’t administered intravenously. To make it so, scientists have modified ibuprofen slightly to alter its properties.
If your DNA is a cookbook of “recipes” your cells could make, microRNAs help decide what’s for dinner.
Title: Peptide Probes for Plasmodium falciparum MyoA Tail Interacting Protein (MTIP): Exploring the Druggability of the Malaria Parasite Motor Complex Authors: Charlie N. Saunders, Ernesto Cota, Jake Baum, and Edward W. Tate Journal: ACS Chemical Biology Year: 2020 Malaria is one of the world’s oldest known…
Cataloguing viruses in bats and other animals may help predict or trace viral transmission to humans in the future.
Researchers develop a new two-layer coating for medical devices that dramatically reduces the chance of infection.
Many molecules can decrease enzymatic breakdown of our body’s natural painkillers…but which one is fit to be the best new drug?
With a growing interest in the field of RNA-targeted therapeutics, robust platforms to study RNA small-molecule interactions are needed. Read about the latest endeavor here!
Infected cattle can transmit E. coli to humans through contaminated ground beef, but scientists are looking for a solution.
Developing a drug that is able to enter the cell and interact with its target is no mean feat, especially for large molecules. Read about how this group ‘masked’ large molecules to improve their cell permeability.
The earthy smell of soil originates from the bacteria that live there. But why do they produce this particular scent?
Tired of consuming 5 different medications a day? Read how the researchers are developing new ways to load different drugs in a single delivery system.
Instead of the wires, batteries, and light bulbs used in electric circuits, biochemical circuits use DNA and enzymes to get the job done.
Researchers developed a new way of tackling viral infection by designing nanostructures similar in shape to the virus particle.