Their highly specialized roles of immune cells also mean they have molecular machineries that are a bit different from those in other cells, Find out here how researchers are using chemistry to advance our knowledge of one of such components, the immunoproteasome.
Chemistry & COVID-19
The COVID-19 pandemic is consuming our news feed at the moment – while you’re self-isolating read about some of the great science research going on to combat our newest virus.
Putting chemists out of business- the immunotherapy revolution
The development of chemotherapy revolutionised the treatment of cancer in the 20th century, however, side effects have remained problematic. Immunotherapy, using the body’s natural immune system to fight cancer, may be a safer and more effective alternative.
Downstream Effects of Adding Hydrochar Nutrients to Soil
Thermochemical degradation of plant matter can create a great plant fertilizer called hydrochar. But what effect does this hydrochar have on the soil ecosystem?
Seeing the Invisible
Ever wondered how scientists know what is going on inside a cell, or how you could design a chemical probe to tell you more? There’s a lot of things to consider, find out more here.
Vanilla substitute loosens up cell membranes to increase drug uptake
Could vanillin, the flavoring molecule extracted from vanilla bean, increase our body’s ability to absorb ingested drugs?
Stitching proteins together, piece by piece
New technology developed to build larger proteins
Rapidly Developing Disease-Specific Detection Methods
Antibodies in your body help fight disease by specifically targeting a viral or bacterial strain. This specificity makes antibodies useful for disease detection, but how do scientists reduce the chance of false positives and false negatives?
Controversial Mushrooms Can Be Useful After All
With a renewed interest in psilocybin — the psychedelic substance present in magic mushrooms — by the medical community, the Weng group at MIT sets up to study one of the enzymes that makes it.
How Long Do Nanoparticles Stay in the Body?
As nanotechnology is developed into drugs for human health, scientists need to study nanoparticle clearance rates from the body.
Development of Sensors for Amino Acids
Researchers develop an easy to use method to identify the chirality of the amino acids, amines and alcohols.
Detergents are for more than washing dishes
Studying membrane-bound proteins requires stabilizing their structure outside of the membrane – otherwise they fall apart. But our analytical techniques have not risen to the challenge. Sadaf et al. pushes us forward by developing novel detergents for stabilizing membrane proteins.
Edible microorganism: the food of the future?
A group from the University of Tübingen obtained single-cell proteins with circular resources and renewable energy.
More than just our genetic code: how chemical modifications affect gene expression
DNA is the instruction manual for how to produce an organism, one gene at a time. But our heart cells, liver cells, and brain cells are different, despite having the same DNA, thanks in part to the “epigenetic” modifications that control which genes are expressed.
Now slide real smooth: Using peptide coatings to prevent biofilm formation
When it comes to milk, preventing bacterial contamination on dairy equipment is key. Researchers in Israel developed a biological coating to prevent biofilm formation and keep their moo-juice fresh and clean.
Delicious diagnosis – real-time glucose analysis straight from your gut
Scientists from UCSD and Compultense University developed non-invasive tools to measure gastrointestinal distress, monitoring chemical markers in real-time.
Nanoparticle Made of DNA Degrades Cancerous HER2 Protein
DNA can be more than just the genetic code. Can four specially designed strands of DNA destroy cancer cells?
Smelling chemicals with an artificial nose
Nothing compares to a well-trained dog’s nose for smelling out faint odors. But a new artificial nose made with living cells may come close!
Finding Genes that Fit: Targeting DNA Bases
Changes in our DNA can cause a host of health issues. However, we can mitigatge a lot of those if we can identify and catalogue these changes, potentially developing novel treatments.
Manipulating actinomycetes for unusual antibiotics
Scientists genetically modify bacteria to overproduce uncommon antibiotics, revealing information on how bacteria regulate and modify its metabolites.
Fishing for bacteria with gold and DNA
What happens when you bring DNA strands, gold nanoparticles, conformation-induced color changes, and a highly-intrusive bacterium together? A field-portable, inexpensive test for the world’s greatest bacterial threats.
Using microbes to make natural products
Microbial systems can be a great way to make complicated products that are useful to humans. However, because the pathways to make these products involve multiple steps and can be very complex, sometimes it’s just too difficult for one species to accomplish on its own. But working as a team with another species of microbe can have its own problems. How can researchers decide which way is best?
Did life come from the depths of the ocean?
Amino acids were found in the Atlantis Massif, under the ocean floor. Is their non-biological synthesis the origin of life?
Ancient biochemistry—your four billion year old ribosome!
Four billion years ago the Earth cooled, cyanobacteria gave us our oxygen-rich atmosphere, and your ribosomes started synthesizing proteins!
New Insights on The Elusive Protein Sulfinylation
Proteins bear a staggering collection of small chemical modifications that have large effects on their function. This research provides an elegant method to study cysteine sulfinylation, a chemical mark that has proven to be pretty elusive.