Many molecules can decrease enzymatic breakdown of our body’s natural painkillers…but which one is fit to be the best new drug?
Category: molecular
Pathogenic E. coli Can Survive Stomach Acid…For Now
Infected cattle can transmit E. coli to humans through contaminated ground beef, but scientists are looking for a solution.
Masked Entry – Increasing cell permeability of large molecules
Developing a drug that is able to enter the cell and interact with its target is no mean feat, especially for large molecules. Read about how this group ‘masked’ large molecules to improve their cell permeability.
Molecular tweezers pick viral membranes apart
While most scientists search for specific treatments for viruses like Ebola, Zika and SARS-Cov-2, non-specific methods can have broad impact. Researchers from the United States and Germany joined forces to make non-specific molecular “tweezers” that pluck pieces out of its membrane, leading to disintegrating and dead viruses.
The Smell of Rain Has a Biological Function
The earthy smell of soil originates from the bacteria that live there. But why do they produce this particular scent?
Life in the Hot Springs: Bacterial Tricks for Thermal Stability
When cooking an egg, heat denatures proteins in the egg. How does a thermophilic bacteria prevent its proteins from denaturing too?
Visualising Chemistry
Appreciating the 3D structure of the tiny chemical compounds we work with can be really difficult – but what if you could project the structure onto your living room floor?
Better Antibiotics: Active in the Body, Degraded in the Environment
Antibiotics are lifesaving, but current practices don’t keep them from accumulating in the environment where they can damage nature and human health. A new antibiotic design aims to solve this problem.
Chemistry & COVID-19
The COVID-19 pandemic is consuming our news feed at the moment – while you’re self-isolating read about some of the great science research going on to combat our newest virus.
Rapidly Developing Disease-Specific Detection Methods
Antibodies in your body help fight disease by specifically targeting a viral or bacterial strain. This specificity makes antibodies useful for disease detection, but how do scientists reduce the chance of false positives and false negatives?
How Long Do Nanoparticles Stay in the Body?
As nanotechnology is developed into drugs for human health, scientists need to study nanoparticle clearance rates from the body.
“Uncorking” a Mini Machine
Scientists discover a novel mechanism for taking apart tiny machines
More than just our genetic code: how chemical modifications affect gene expression
DNA is the instruction manual for how to produce an organism, one gene at a time. But our heart cells, liver cells, and brain cells are different, despite having the same DNA, thanks in part to the “epigenetic” modifications that control which genes are expressed.
Nanoparticle Made of DNA Degrades Cancerous HER2 Protein
DNA can be more than just the genetic code. Can four specially designed strands of DNA destroy cancer cells?
Filling the p-hole: Using a tetrel bond to better understand SN2 chemistry
Using a new model of a tetrel bond to further probe the mechanism of an SN2 reaction.
Antibacterial Screening In Live Cells: In Search Of Life-Saving Drugs
Just as interesting as the detail of how the antibacterial molecules works can be the new methods by which they are discovered. Today’s Chembite is about the development of antibacterial agents in the fight against an infectious bacterium.
Discovering Novel Structures – A molecular fidget spinner?
While discovery of new complexes can be difficult, this group at Cambridge has developed “cube traps” and effectively synthesized a molecule atkin to a molecular fidget spinner!
From Sunscreen to Solar Cells: What’s Happening on TiO2‘s Surface?
The controversy over TiO2’s hydrophilic/hydrophobic transition has been examined in new detail – with researchers concluding that atmospheric molecules can attach onto TiO2’s surface, changing its chemical properties.
Destroying Rogue Kinases with Degraders
Aberrant enzyme activity drives many types of cancer and other human diseases. Traditional drugs targeting such enzymes face a variety of challenges. Here, researchers use a new small molecule “degrader” to destroy an enzyme involved in cancer.
Capturing a new form of DNA: i-motif DNA structures and where to find them
A new form of DNA was found in vivo. It can be a way to regulate the DNA replication and thus prevent the replication of tumor cells.
Sniffing Sensors to Save Entrapped Humans
Human odors and skin oils can be detected by hand-held sensors in order to aid in urban search and rescue efforts.
Making computers from molecules – Molecular Turing Machines
In this article, explore the tiny molecules that could be used for computational work in future of smartphones! Inspired by your own body, machines made from molecules could be the next generation of computers!